Danielle A. Schlosser, PhD

Danielle A. Schlosser, PhD
PhD, California School of Professional Psychology
Assistant Professor of Psychiatry, Department of Psychiatry, UCSF
Faculty, NIH mHealth Training Institute
Director, Digital Health Core, Department of Psychiatry, UCSF
Phone: (415) 476-8721
Fax: (415) 476-7320
Email: Danielle.Schlosser@ucsf.edu

UCSF Profiles

DRIVE (The Digital Research and Interventions for Volitional Enhancement) Laboratory

Digital Health Core

Research Interests:

Currently, I hold the positions of Assistant Professor in the Department of Psychiatry at the University of California, San Francisco, Director of the Digital Health Core in the Department of Psychiatry, and I direct the NIMH-funded Digital Research and Interventions for Volitional Enhancement (DRIVE) lab. The goal of my research program is to design, develop, and investigate neuroscience-informed digital health interventions to improve the lives of people with schizophrenia and depression. I have a broad background in clinical psychology, with specific training in behavioral neuroscience, early detection and intervention of psychosis, and digital health research. My research is focused on translating the latest findings in the area of reward processing and psychological determinants of motivation into new interventions to treat individuals with schizophrenia and depression. My focus in on targeting domains that transcend diagnostic labels, such as motivational states and enhancing outcomes, such as quality of life. More recently, with funding from NIMH, my research was focused on developing a mobile app called PRIME, which was designed to target the motivational system and thereby enhance the drive to improve one's quality of life and health outcomes. We are testing the feasibility and impact of PRIME in two ongoing clinical trials in schizophrenia and we recently completed a pilot trial in depression. Two of the three trials were conducted entirely remotely, one with individuals with depression and the other with individuals recently diagnosed with schizophrenia. We recently submitted several grants to extend this work to the population of those struggling with depression and eventually to schizophrenia.

Professional Honors and Awards:

  • 2004 Academic Scholarship (2004-2008), California School of Professional Psychology at Alliant International University
  • 2007 Division 42 Student Poster Award, American Psychological Association 2007 Annual Conference
  • 2009 Ruth Kirschstein National Research Service Award Fellow (2009-2010), National Institute of Mental Health
  • 2011 Research Travel Award, University of California, San Francisco
  • 2011 Ruth Kirschstein National Research Service Award Fellow , National Institute of Mental Health
  • 2012 Mobile Health Research Award, UCSF Clinical and Translational Science Institute
  • 2013 Catalyst Award for Digital Health, UCSF Clinical and Translational Science Institute
  • 2014 Digital Health Research Award, UCSF Clinical and Translational Science Institute
  • 2014 Loan Repayment Award, National Institute of Health
  • 2015 Digital Health Research Award, UCSF Clinical and Translational Science Institute

Selected Publications:

  1. Schlosser, DA, Zinberg JL, Loewy RL, Casey-Cannon S, O’Brien MP, Bearden CE, Vinogradov S, Cannon TD (2010). Predicting the longitudinal effects of the family environment on prodromal symptoms and functioning in patients at risk for psychosis. Schizophrenia Research, 118(1-3), 69-75. PMC2856759.
  2. Schlosser DA, Jacobson S, Chen Q, Sugar CA, Niendam TA, Bearden CE, Cannon TD. (2011) Recovery from an at-risk state: Clinical and functional outcomes of putatively prodromal youth who do not develop psychosis. Schizophrenia Bulletin, doi: 10.1093/schbul/sbr098; PMID: 21825282; PMCID: PMC3494042.
  3. Schlosser DA, Pearson R, Perez V, Loewy RL. (2012) Environmental risk and protective factors and their influence on the emergence of psychosis. Adolescent Psychiatry, 2, 163-171.
  4. Schlosser, D.A., Miklowitz, D., O’Brien, M. P., DeSilva, S., Zinberg, J.L., Cannon, TD. (2012) A Randomized Trial of Family Focused Treatment for Adolescents and Young Adults at Risk for Psychosis: Study Rationale, Design, and Methods. Early Intervention in Psychiatry, doi: 10. 1111/7893.2011; PMID: 22182667.
  5. Fisher M, Loewy RL, Hardy KV , Schlosser DA, Vinogradov S. (2013) Cognitive Interventions Targeting Brain Plasticity in the Prodromal and Early Phases of Schizophrenia. Annual Review of Clinical Psychology, 9, 435-63.
  6. Loewy R, Fisher M, Schlosser DA, Biagianti B, Stuart B, Mathalon DH, Vinogradov S. (2016) Intensive auditory cognitive training improves verbal memory in adolescents and young adults at clinical high risk for psychosis. Schizophr Bull, doi: 10.1093/schbul/sbw009
  7. Schlosser DA, Campellone TR, Castaneda D, Kim D, Truong B, Vergani S, Ward C, Vinogradov S. (2016). Feasibility of a neuroscience-informed mobile app intervention to enhance motivated behavior and improve quality of life in recent onset schizophrenia Journal of Medical Internet Research: Research Protocols, doi: 10.2196/resprot.5450
  8. Schlosser DA, Campellone TR, Biagianti B, Delucchi KL, Gard DE, Fulford D, Stuart BK, Loewy RL, Vinogradov S. (2015). Modeling the role of negative symptoms in determining social functioning in individuals at clinical high risk of psychosis. Schizophrenia Research, doi:10.1016/j.schres.2015.10.136
  9. Schlosser DA, Fisher M, Gard D, Fulford D, Loewy RL, Vinogradov S. (2014). Motivational deficits in individuals at-risk for psychosis and across the course of schizophrenia. Schizophrenia Research, doi: 10.1016/j.schres.2014.06.024.

Complete List of Published Work in MyBibliography: http://www.ncbi.nlm.nih.gov/pubmed/?term=danielle+schlosser